Module
19
Icon module 19

Introduction

The hindgut extends from the left third of the transverse colon to the cloaca (rectum). In contrast to the midgut, no intestinal rotation occurs here but rather this part gets pushed to the left side by the midgut returning from the umbilical coelom.
It consists of:

  • Transverse colon (left third)
  • Descending colon
  • Sigmoid colon
  • Rectum
  • Anal canal

Hindgut

Initially the hindgut dead-ends in the cloaca and is separated by the cloacal membrane from the ectodermal anal pit, the proctodaeum. In addition, at its end, it is connected to the allantois and to the mesonephric duct.
From stage 14, ca. 33 days, the cloaca flattens in the frontal plane and extends somewhat in the sagittal plane, whereby from the upper rear and from both sides a mesenchymal condensation, the urorectal septum, arises in the angle between the allantois and the hindgut. Through this mechanism, the cloaca is subdivided into the urogenital sinus (ventrally) and the anorectal canal (dorsally). (See details about the subdivision of the urorectal septum in the urinary system module).

Fig. 25 - Hindgut in stage 15
(ca. 36 days)
media/module20/t4p1_migr.gif

  1. Anlage of the gonads
  2. Mesonephros
  3. Allantois
  4. Genital tubercle
  5. Cloacal membrane
  6. Cloaca
  7. Hindgut
  8. Metanephros
  9. Mesonephric duct (Wolff's duct)
  10. Ureter

Fig. 26 - Hindgut in stage 18
(ca. 44 days)
media/module20/t4p2_migr.gif

1
Anlage of the gonads
3
Anlage of the bladder
4
Genital tubercle
5
Cloacal membrane
6
Rectum
7
Hindgut
8
Metanephros
9
Mesonephric duct (Wolff's duct)

Legend
Fig. 25

The urorectal septum extends itself caudally (in the direction of the arrow) and subdivides the urorectal sinus into a urogenital sinus and an anorectal canal.

Fig. 26

The urorectal septum has almost reached the perineum.

 

In the cloacal region the urorectal septum thickens still more and forms the material for the deep perineum. In stage 19, ca. 46 days, the cloacal membrane ruptures and the endodermal part of the anal canal goes over into the ectodermal part of the proctodeum.
During this period the anorectal canal is closed by an epithelial plug and is recanalized again only in the early fetal period.

Fig. 27 - Hindgut in stage 23
(ca. 56 days)
media/module20/t4p3_migr.gif

1
Anlage of the gonads
3
Anlage of the bladder
4
Genital tubercle
6a
Rectum
7
Hindgut
8
Metanephros
9
Mesonephric duc (Wolff's duct)
10a
Ureter
11
Urogenital orifice
12
Anal orifice

Legend
Fig. 27

The separation is now complete and the cloacal membrane ruptures in this stage.

More info

The first villi and Lieberkühn's glands arise in the early fetal period. However, they disappear shortly before birth and appear again only after birth. With the beginning of the second trimester the meconium in the large intestine is formed. It consists of dark green material that mainly consists of a mixture of secretions of the intestinal glands and the gall bladder as well as of amniotic fluid, which is swallowed by the fetus. The intestinal content is sterile up to birth. Following birth the meconium is passed as the first stool by the newborn.