Icon module 9

Fetal period

According to estimates, over 90% of the 4500 designated structures of the adult body are already established - and can be distinguished - during the embryonic period. During the fetal period the organs that formed during the embryonic period grow and differentiate (organogenesis).

Figure 2 shows the various temporal phases during a pregnancy. A rough classification is made by assigning trimesters (trimenon). The LMP (Last Menstruation Period) is not the real beginning of the pregnancy but serves as a point of reference for determining the date of ovulation and thus the moment of fertilization. Normally this occurs 14 days after the beginning of menstruation, but can vary a lot temporally. From the time of the last period, one estimates 40 weeks after the last menstruation in order to determine the approximate date of birth (the second and third grid marks represent the lunar month [of 28 days] or 4 weeks). On average, though, the duration of an actual pregnancy amounts to 266 days or 38 weeks (fourth grid). The embryonic period (A) lasts 8 weeks and the fetal period (B) from the 9th week to the birth.

Fig. 2 - Time calculations during a pregnancy

Embryonic period
Fetal period

Fig. 2

The schematic diagram shows the various time periods during the entire pregnancy.
LMP = Last Menstruation Period.
The embryonic period (A) lasts 8 weeks and the fetal period (B) from the 9th week to the birth, i.e., 30 weeks.

In obstetrics the pregnancy weeks (PW) are normally reckoned from the date of the Last Menstrual Period (LMP). This is a point in time that many women can easily remember. Computed this way, the pregnancy lasts 40 weeks and the embryonic period - accordingly - 10 weeks. Caution is advisable, though, when wishing to calculate the moment of ovulation - and thus fertilization, closely connected with it - because the moment of ovulation can vary and depends on many factors (conditioned by the environment and psychological aspects). In embryology the temporal indices (i.e., the PW), therefore, always refer to the moment of fertilization even though in practical midwifery the time following the LMP is still used for computations.

After the 8th week, the fetus takes on typical human features, even though at the end of the first trimenon, the head is still relatively large in appearance. The eyes shift to the front and the ears and nasal saddle are formed.
The eyelids are also clearly recognizable now. On the body, fine lanugo hairs are formed, which at the time of birth are replaced by terminal hairs. The physiologic umbilical hernia that arises in the embryonic period (stages 15-20) has mostly disappeared.
In the second trimenon the mother feels the first movements of the child. In the last trimenon the subcutaneous fatty tissue is formed and stretches the still wrinkled skin of the fetus. The skin becomes covered more and more with vernix caseosa. This is a whitish, greasy substance und consists of flaked off epithelial cells and sebaceous gland secretions. In neonatology this vernix caseosa is an important criterion for judging the maturity of the child. If the birth occurs post-term, it disappears again.

Fig. 3 - Fetus at 8 weeks

  1. Umbilcal cord with hernia
  2. Nose
  3. Eye
  4. Eyelid
  5. Ear (a: tragus, b: antitragus )
  6. Mouth
  7. Elbow
  8. Finger
  9. Toes
  10. Atrophied embryonic tail bud
Spinal cord

Fig. 3

The fetus still has a large head in relation to the rest of the body.

© Professor Kohei Shiota, Kyoto University