Two phenomena mark the differentiation of the canals of the internal male sex organs:
- The atrophy of the paramesonephric duct (Müller)
- The development and differentiation of the mesonephric duct (Wolff)
The mesonephric duct (Wolff) atrophies cranially and leaves behind only the epididymal appendage as an embryonic rudiment. On both sides the parts of the mesonephric duct, which lie across from the testes, form the epididymis. The testis and the epididymis of both sides are partially enveloped by the tunica vaginalis testis (serous bilaminar membrane with a periorchium [ = outermost layer] and epiorchium [ = inner layer]). In the part of the epididymis are end the efferent ductules. They originate from the mesonephric tubules, and so form the beginning of the epididym. Immediately afterwards it coils tightly and finally goes into the lower part of the epididymis (its tail) and over into the deferent duct. This is a musculo-epithelial tube that, during ejaculation, dispatches the sperm cells from the epididymis into the urethra.
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